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Fifth Avenue is renowned for its high-end shopping and luxury boutiques, making it a premier shopping destination not just in New York City, but around the world. Stretching from Washington Square Park in Greenwich Village to uptown, this avenue is home to flagship stores of prestigious brands like Gucci, Louis Vuitton, and Tiffany & Co. Additionally, landmarks such as Saks Fifth Avenue and the iconic Apple Store contribute to its reputation as a shopping mecca.

Madison Avenue, while associated with luxury and high-end brands, is particularly known for advertising agencies and certain boutiques, but it does not hold the same level of shopping fame as Fifth Avenue. Park Avenue is primarily known for its residential buildings and office spaces, showcasing some of the wealthiest neighborhoods but lacking in prominent retail. Broadway is famous for its theaters and entertainment, rather than retail shopping. Thus, Fifth Avenue clearly stands out as the quintessential choice for high-end shopping and boutiques.